ORBIMED ADVISORS LLC is an institutional investment manager that files quarterly 13F reports with the SEC. As of Q4 2025, the fund manages $4.9B in reported equity holdings across 105 positions. The largest holdings are EWTX (7.9%), LLY (6.6%), BSX (4.7%), SVA (3.8%), ELAN (3.5%). The portfolio is concentrated in Other (86.5%), Healthcare (13.5%). Data sourced from SEC EDGAR 13F filings (CIK 1055951).